Assembly and plasticity of neuronal circuits

The human brain is a very complex neuronal circuit. How does this circuit wire up during development?

The major focus in the lab is to understand the circuits present in the developing brain and their influence of brain development and plasticity. One focus is on probing the response of the developing brain to sensory stimuli and the other is to record from small sub-circuits and study their responses and circuit behavior in great detail. We are particularly interested in the relationships of mechanisms and circuits that underlie developmental plasticity and circuits and mechanisms that underlie memory and plasticity in adults. We are addressing these issues by studies in the primary auditory and visual cortex.